Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue
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منابع مشابه
Platelet monoamine oxidase and plasma amine oxidase in psychiatric patients.
Platelet monoamine oxidase (MAO) and plasma amine oxidase (PAO) activities were determined in 70 normal controls and 76 psychiatric patients. Platelet MAO activity did not differ between the normal controls and patients diagnosed as schizophrenic or primary affective illness, although there was a strong trend for chronic schizophrenics to have lower MAO activity. Schizophrenic patients with Sch...
متن کاملHuman Plasma Monoamine Oxidase
Although this human plasma enzyme was shown (1) to have certain characteristics in common with plasma amine oxidases from other mammals (2-6), it could be distinguished from these other plasma enzymes by its substrate specificity. During studies relating to the substrate specificity of the human enzyme, the oxidation of aliphatic amines was noted to have a number of distinctive kinetic features...
متن کاملHuman Plasma Monoamine Oxidase
Amine oxidases that occur in the plasma of mammals have been intensively studied in recent years (l-8). The ability of human plasma and serum to convert benzylamine to benzaldehyde has recently been demonstrated (9). Evidence has been presented to show that this enzymatic activity is different from other human plasma enzymes that catalyze the oxidation of amines (i.e. ceruloplasmin and diamine ...
متن کاملAn evaluation of phospholipids as regulators of monoamine oxidase A and monoamine oxidase B activities.
When rat liver mitochondria are treated with the phospholipase A2 isolated from Naja naja venom in amounts sufficient to cause about 70% loss of mitochondrial phospholipids, both of the monoamine oxidase isozymes monoamine oxidase A and monoamine oxidase B are reduced in activity. With both monoamine oxidases, phospholipase treatment affects the enzyme’s affinity for the amine substrates rather...
متن کاملMonoamine oxidase inhibitory activities of heterocyclic chalcones.
Studies have shown that natural and synthetic chalcones (1,3-diphenyl-2-propen-1-ones) possess monoamine oxidase (MAO) inhibition activities. Of particular importance to the present study is a report that a series of furanochalcones acts as MAO-B selective inhibitors. Since the effect of heterocyclic substitution, other than furan (and more recently thiophene, piperidine and quinoline) on the M...
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ژورنال
عنوان ژورنال: Medicines
سال: 2020
ISSN: 2305-6320
DOI: 10.3390/medicines7040018